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Research Interests

Metalloenzymes for Drug Targets

Ribonucleotide Reductases
Glycyl Radical Enzymes and the Human Gut

Metalloenzymes that Make Vitamins, Antibiotics and Other Natural Products

Structure/Function Relationships in Radical SAM Enzymes
Structure/Function Relationships in Mononuclear Nonheme Iron Enzymes

Metalloenzymes and the Environment

Life on CO2: Structural Elucidation of the Wood-Ljungdahl Pathway
Pollutant Metabolism by Glycyl Radical Enzymes

Metalloproteins as Transcriptional Regulators

Cobalamin as a Light Sensor in Gene Regulation

Metalloenzyme Assembly

Metallochaperones for Cobalamin-dependent Maturation
Iron Sulfur Cluster Biogenesis and Delivery

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